Discovery Accelerated
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Removing Plaque from Alzheimer Brains

January 15, 2010 06:10 by asischemadmin

January 2010 Newsletter  


I hope everyone had a joyous holiday season!  Though some of you might have had a fantastic 2009 I am betting the majority of us are looking forward to a more prosperous 2010.  To start us of on the right foot we are co-hosting a workshop in the Boston area focused on obtaining funding for drug discovery projects.  If you are in the area we would love to see you.  If not, you can always contact Mel Bellott for information about:

  • The value of early ADMET screening of candidate compounds
  • How medicinal chemistry efforts contribute to your program's success
  • Developing a program framework for drug discovery
  • Lead compound strategy


As always enjoy!

Chemistry (The Dork Song) (click for video)

"Nano Cocktail" to Target and Kill Tumors A team of researchers in California and Massachusetts has developed a "cocktail" of different nanometer-sized particles that work in concert within the bloodstream to locate, adhere to and kill cancerous tumors. Read More

Nanoparticles Bypass Mucus Barrier, May Deliver Drugs  Johns Hopkins University researchers have created biodegradable nanosized particles that can easily slip through the body's sticky and viscous mucus secretions to deliver a sustained-release medication cargo. The researchers say that these nanoparticles, which degrade over time into harmless components, could one day carry life-saving drugs to patients suffering from dozens of health conditions, including diseases of the eye, lung, gut or female reproductive tract. Read More

Scientists Remove Plaque from Brains with Alzheimer's Disease A breakthrough discovery by scientists from the Mayo Clinic in Jacksonville, FL, may lead to a new treatment for Alzheimer's Disease that actually removes amyloid plaques-considered a hallmark of the disease-from patients' brains. This discovery, is based on the unexpected finding that when the brain's immune cells (microglia) are activated by the interleukin-6 protein (IL-6), they actually remove plaques instead of causing them or making them worse. The research was performed in a model of Alzheimer's disease established in mice. Read More 

I know there are projects that need custom synthesis, medicinal chemistry or chemical consulting. Why wait any longer submit an inquiry!



Bryan Roland,

Director - Project Management

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