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Chemistry of Chocolate and Roses

February 11, 2010 10:55 by GregRublev

This is the most popular newsletter in our history.  I suppose it makes sense: who doesn't like chocolate or roses?  Hope valentine's day goes off without a hitch for everyone!

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February 2010 Newsletter 

Greetings!

February is here and with it Valentine's Day.  Bad food, long waits and poor service.  But if you get past all of the force feed love there is a lot of chemistry.  The video touches on some interesting chemistry with chocolate and roses. Enjoy.

Chocloate and Roses
CHICAGO --- A researcher from Northwestern University Feinberg School of Medicine has invented a novel way to halt and even reverse rheumatoid arthritis. He developed an imitation of a suicide molecule that floats undetected into overactive immune cells responsible for the disease.

Whimsically referred to as Casper the Ghost, the stealthy molecule causes the immune cells to self-destruct. Read More 

A new therapeutic made from tobacco plants has been shown to arrest West Nile virus infection, according to a new study by Arizona State University scientist Qiang Chen and his colleagues.

Chen, a researcher at Arizona State University's Biodesign Institute and professor in the College of Technology and Innovation, on the Polytechnic campus, is the first to demonstrate a plant-derived treatment to successfully combat West Nile virus after exposure and infection. The research appears in this week's issue of the Proceedings of the National Academy of Sciences (advanced online edition). Read More 

 

I know there are projects that need custom synthesis, medicinal chemistry or chemical consulting.  Why wait any longer submit an inquiry or use our Ask-A-Chemist service! 

Sincerely, 
Bryan Roland, Director - Project Management 
Bryan.Roland@asischem.com

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Removing Plaque from Alzheimer Brains

January 15, 2010 06:10 by asischemadmin

January 2010 Newsletter  

Greetings!

I hope everyone had a joyous holiday season!  Though some of you might have had a fantastic 2009 I am betting the majority of us are looking forward to a more prosperous 2010.  To start us of on the right foot we are co-hosting a workshop in the Boston area focused on obtaining funding for drug discovery projects.  If you are in the area we would love to see you.  If not, you can always contact Mel Bellott for information about:

  • The value of early ADMET screening of candidate compounds
  • How medicinal chemistry efforts contribute to your program's success
  • Developing a program framework for drug discovery
  • Lead compound strategy

 

As always enjoy!


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Chemistry (The Dork Song) (click for video)




"Nano Cocktail" to Target and Kill Tumors A team of researchers in California and Massachusetts has developed a "cocktail" of different nanometer-sized particles that work in concert within the bloodstream to locate, adhere to and kill cancerous tumors. Read More

Nanoparticles Bypass Mucus Barrier, May Deliver Drugs  Johns Hopkins University researchers have created biodegradable nanosized particles that can easily slip through the body's sticky and viscous mucus secretions to deliver a sustained-release medication cargo. The researchers say that these nanoparticles, which degrade over time into harmless components, could one day carry life-saving drugs to patients suffering from dozens of health conditions, including diseases of the eye, lung, gut or female reproductive tract. Read More

Scientists Remove Plaque from Brains with Alzheimer's Disease A breakthrough discovery by scientists from the Mayo Clinic in Jacksonville, FL, may lead to a new treatment for Alzheimer's Disease that actually removes amyloid plaques-considered a hallmark of the disease-from patients' brains. This discovery, is based on the unexpected finding that when the brain's immune cells (microglia) are activated by the interleukin-6 protein (IL-6), they actually remove plaques instead of causing them or making them worse. The research was performed in a model of Alzheimer's disease established in mice. Read More 


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I know there are projects that need custom synthesis, medicinal chemistry or chemical consulting. Why wait any longer submit an inquiry!

Sincerely,

 

Bryan Roland,

Director - Project Management

Bryan.Roland@asischem.com


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Nano-Scale Drug Delivery For Chemotherapy

November 6, 2009 06:50 by asischemadmin

November 2009 Newsletter  

Greetings!

We have very exciting news this month. AsisChem now has a blog! This newsletter is now posted for access at anytime (and you can look back at old issues with fond memories). Also, we will have articles, commentary and other extremely important and interesting information. So enjoy this newsletter and sign-up to receive notifications of blog updates.
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Organic Reactions Song (click for video)


This Is Your Brain On Fatty AcidsSaturated fats have a deservedly bad reputation, but Johns Hopkins scientists have discovered that a sticky lipid occurring naturally at high levels in the brain may help us memorize grandma's recipe for cinnamon buns, as well as recall how, decades ago, she served them up steaming from the oven. Read More

Slimming Gene Regulates Body Fat Scientists at the University of Bonn have discovered a previously unknown fruit fly gene that controls the metabolism of fat. Larvae in which this gene is defective lose their entire fat reserves. Therefore the researchers called the gene 'schlank' (German for 'slim'). Mammals carry a group of genes that are structurally very similar to 'schlank'. They possibly take on a similar function in the energy metabolism. The scientists therefore have hopes in new medicines with which obesity could be fought. Read More

Nano-Scale Drug Delivery For ChemotherapyGoing smaller could bring better results, especially when it comes to cancer-fighting drugs. Duke University bioengineers have developed a simple and inexpensive method for loading cancer drug payloads into nano-scale delivery vehicles and demonstrated in animal models that this new nanoformulation can eliminate tumors after a single treatment. After delivering the drug to the tumor, the delivery vehicle breaks down into harmless byproducts, markedly decreasing the toxicity for the recipient. Read More


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I know there are projects that need custom synthesis, medicinal chemistry or chemical consulting. Why wait any longer submit an inquiry!

Sincerely,

Bryan Roland,

Director - Project Management

Bryan.Roland@asischem.com


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Brain Proteins Suggest Possible Way to Fight Alzheimer's

October 8, 2009 23:23 by asischemadmin

October 2009 Newsletter  

Greetings!

Happy Mole Day! I suppose have a scary Halloween as well. I don't know what is going on for Halloween, but I am definitely celebrating Mole day with Chicken Mole from my favorite Mexican restaurant (an old tradition from my time in Tucson, Az). I hope whichever holiday you choose to participate in you enjoy it as much as I will. Anyway, there were so many interesting research articles to choose from this month I just chose a few I thought you might like. Enjoy.

The Mole Song



Brain Proteins Suggest Possible Way to Fight Alzheimer's

DALLAS - Oct. 6, 2009 - The action of asmall protein that is a major villain in Alzheimer's disease can becounterbalanced with another brain protein, researchers at UT Southwestern Medical Center have found in an animal study.

The findings, available online in the journal Proceedings of the National Academy of Sciences, suggest a promising new tactic against the devastating illness, the researchers said. Read More

How Soy Reduces Diabetes Risk

AMHERST, Mass. -Nutrition scientists led by Young-Cheul Kim atthe University of Massachusetts Amherst have identified the molecularpathway that allows foods rich in soy bioactive compounds calledisoflavones to lower diabetes and heart disease risk. Eating soy foodshas been shown to lower cholesterol, decrease blood glucose levels andimprove glucose tolerance in people with diabetes. Read More

A Step Toward Better Brain Implants Using Conducting Polymer Nanotubes

ANN ARBOR, Mich.-Brain implants that can more clearly record signalsfrom surrounding neurons in rats have been created at the University ofMichigan. The findings could eventually lead to more effectivetreatment of neurological disorders such as Parkinson's disease andparalysis. Neural electrodes must work for time periods ranging from hours toyears. When the electrodes are implanted, the brain first reacts to theacute injury with an inflammatory response. Then the brain settles intoa wound-healing, or chronic, response. Read More

Please send us some questions, inquiries, challenges or anything else chemistry related. Put our expert chemists to the test by submitting an inquiry!

Sincerely,
Bryan Roland, Director - Project Management
Bryan.Roland@asischem.com

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