June 2010 Newsletter
Dear Bryan,
Last month Mel Bellott
from AsisChem was
invited to UCSF to
give a seminar on Drug Discovery. His presentation used case studies
and examples to show how chemistry is involved from
beginning-to-end. The talk illustrated some of the important
opportunities and pitfalls along the way to advancing a new drug
candidate.
Due to the overwhelming positive response, we are giving a webinar on
June 23 at 10:30 AM PST. To find out more please visit our registration page.
Molecular Imaging Reveals Origin of
Acid
Reflux Disease
Molecular imaging has
uncovered what may be to blame for acid reflux
disease, a painful and potentially dangerous illness that affects a
sizeable percentage of the population. A study presented at SNM's 57th
Annual Meeting provides further evidence that the disease of the
digestive system is brought on by a lack of tone, or motility, in the
esophageal muscles that clear and keep stomach acids and other gastric
contents from backing up into the esophagus. Read More
Ancient
Viral Invasion Shaped Human
Genome
Scientists
at the Genome Institute of Singapore, a biomedical research institute
of the Agency for Science, Technology and Research, and colleagues have
recently discovered that viruses that "invaded" the human genome
millions of years ago have changed the way genes get turned on and off
in human embryonic stem cells. The study provides definite proof of a
theory that was first proposed in the 1950's by Nobel Laureate in
physiology and medicine, Barbara McClintock, who hypothesized that
transposable elements, mobile pieces of the genetic material, such as
viral sequences, could be "control elements" that affect gene regulation
once inserted in the genome.
Read More
Scientists
Break Barrier to Creating
Potential Therapeutic Molecules
Scientists from The Scripps
Research Institute have created a novel
technique that for the first time will allow the efficient production of
a molecular structure that is common to a vast array of natural
molecules. This advance provides a means to explore the potential of
this molecular substructure in the search for new therapies. Read More
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